Tuesday, May 13, 2014

1. Dysentery
- Culture and treat with appropriate antibiotics
Typical organisms: 
- Campy
- Salmonella
- E.coli (STEC- makes shiga toxin, EIEC - similar to shigella)
- Shigella
- C.Diff
2. Campy
- Often has prodrome, flu like illness
- Azithro 
3. Salmonella
- Turtles, reptiles
- Cipro 
4. STEC e.coli (O157-H7) aka EHEC 
- No fever, only bloody diarrhea, a lot of abdominal pain 
- Cecal/colonic wall thickening - Can present clinically like appendicitis
- Don't treat, just let it run its course-- In kids, the data seems to show that the ones who get antibiotics are more likely to get HUS 
5. Shigella
- Tends to be more L sided. 
- Cipro 
6. C.Diff
- There exists community acquired C.diff
- If someone comes in w bloody diarrhea, send c.diff toxin as well 
- PPIs/NSAIDs are also linked-- PPIs are almost as closely linked as antibiotics 
7. Community antibiotic-associated minor diarrhea without blood
- stop the antibiotics 
- Likely just a consequence of changing bowel flora, give probiotics
- In community, odds of C.diff in sb on antibiotics with diarrhea ~15%
8. Giardia
- Recreational water facilities 
- Treat empirically with flagyl, as it's notoriously hard to find/culture from the stool. 
9. Algorithm for diagnosing diarrhea: 

10. Types of E.Coli:
- STEC : shiga-toxin producing e-coli (O157-H7) formerly known as EHEC and many others
- ETEC : enterotoxigenic e.coli - watery, traveler's
- EPEC : enteropathogenic e.coli- watery diarrhea in adults and kids 
- EIEC : enteroinvasive, bloody diarrhea with tenesmus, similar to Shigella
- EAEC : enteroaggregative - a different cause of traveler's diarrhea 

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