Tuesday, January 14, 2014

1. Dementia w Lewy bodies can present like schizophrenia with hallucinations and flat affect, don't use haldol, use seroquel
2. Frontotemporal dementia: can present as dis-inhibition or as social withdrawal
3. Depression in the context of Alzheimer's:
-Sertraline 25, go to 50 in a week. GI side effects
-Citalopram well tolerated.
-SIADH as a side effect of SSRI more likely to occur in old people
4. Anxiety in the context of Alzheimer's: 
-NO BENZOS, avoid at all costs.
-Risperidone or seroquel (nice sedating effect, help them sleep)
5. Insomnia in the context of Alzheimer's:
-Trazodone: does not maintain sleep architecture.
-Seroquel
-Mirtazapine: maintains sleep architecture, grants refreshing sleep, increases appetite.
6. Diagnosing PTSD: 4 clusters of symptoms
-Reliving the experience (flashbacks, nightmares)
-Avoidance of things that remind of the experience
-Hyperarousal (hypersensitive to sound, light)
-Affect changes (irritability, etc)
-Sx can occur at any time after trauma, must last >4 weeks.
7. Schizotypy: 
-Impaired smooth pursuit (reflects problems with working memory): correlates with negative symptoms
-Negative symptoms correlate with brain mass loss
-General defects with auditory and tactile perception
-Defect of forming safe "personal space" in their head-- they feel like people who get close can invade into the deepest parts of them.
-Worsen with NMDA antagonists and D agonists.
8. Criteria for personality disorder: 2 or more of the following categories are compromised:
-Cognition (delusions, paranoia)
-Mood/affect
-Interpersonal relationships
-Impulsivity
9. Units of measure of alcohol (approx)
-Pint: 375 mL
-Fifth: 750 mL
-Handle: 1.75 L
10. Amount of alcohol in mouthwash: 0-27%. 

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